Examining the cognitive effects of a special extract of Bacopa monniera (CDRI08: Keenmnd): A review of ten years of research at Swinburne University

Con Stough, Andrew Scholey, Vanessa Cropley, Keith Wesnes, Andrea Zangara, Matthew Pase, Karen Savage, Karen Nolidin, Luke Downey1

1Department of psychology, Swansea university, Wales, UK

Abstract


Bacopa monniera (EBm), an Indian aquatic herb, has been used in traditional Ayurvedic medicine for centuries for indications related to memory and inflammation. More recently specific extracts of EBm have emerged that have been subjected to rigorous in vitro, animal and now human clinical trials. In this paper we discuss some of these studies with special reference to mechanisms and efficacy of a special extract of Bacopa (CDRI08). Studies using this extract indicate that CDRI08 has several modes of action on the human brain. Promising indications for use in humans include improving cognition in the elderly and in patients with neurodegenerative disorders.

J Pharm Pharm Sci, 16 (2): 254-258, 2013

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